近视的最新研究进展形觉剥夺Form

白癜风早期症状 http://www.bflvye.com/
Overthelastfourdecades,numerousanimalmodelshaveprovidedvaluableinsightintothemechanismsunderlyingemmetropizationandrefractiveerrordevelopment.Muchoftheknowledgeonvision-dependentchangesinoculargrowthhasemanatedfromanimalexperimentsinwhicheitherthequalityofimageformedontheretinaisdegraded(knownasform-deprivation[FD]),orthefocalpointoftheimageisalteredwithrespecttotheretinalplane(knownaslensinduceddefocus).BothFDandlensinduceddefocusresultinabnormaleyegrowthanddevelopmentofrefractiveerrors.Thissectionsummarizestheattributesofexperimentalametropiasderivedfromthesetwovisualmanipulations,theirdifferences,andsignificanceforunderstandingrefractiveerrordevelopmentinhumans.在过去的40年里,许多动物模型为正视化和屈光不正发展机制提供了有价值的见解。关于依赖视觉引起的眼球生长的许多知识源于动物实验,在动物实验中,视网膜上形成的图像质量下降(称为形觉剥夺[FD]),或者图像的焦点相对于视网膜平面改变(称为镜片诱导离焦)。FD和镜片诱导离焦都会导致眼睛异常生长和屈光不正。本节总结了从这两种视觉操作中得出的实验性屈光不正的属性,它们的区别以及对理解人类屈光不正的重要性。Form-DeprivationMyopiaFDisthemost


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